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AOD9604

AOD9604

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AOD9604

Availability: In stock

$35.99

Availability: In stock

$35.99
Description

What is AOD9604?


All the information below is strictly for research purposes only. Under no circumstance should this chemical be used for human consumption.


AOD9604 is a synthetic peptide that consist 14 amino acids. Also called as tyr-somatostatin, AOD9604 stimulates lipolysis and suppress lipogenesis without influencing growth or causing insulin resistance. The compound is regarded as a growth hormone analogue. Experimental studies were conducted by the scientists at Monash University to investigate the effects of the compound on obesity. The researchers found that the compound selectively target obese fat cells but not lean fat cells. Being rich in proline and proteases, AOD9604 exerts several cellular changes in cytoplasm. The hypolipidemic property of the investigative compound is being studied by the research community. The compound’s molecular weight is 1815.1 and molecular formula is C78H13O23S2.


The studies carried on the peptide AOD9604 for their ability to increase blood glucose and sustain blood insulin, which in turn helps in reduction of lipogenesis a process, which induces depositing of fats on the visceral and peripheral organs. The informational sequence is highly influential in presenting regions of high protein accessibility to the receptors. Research shows that the HGH fragment releasing fats are inhibited by the introduction of the polypeptide, moreover it does not induce growth or change food consumption.   AOD9604 increases muscle mass, reduce excess adipose tissues in the abdominal area and increases the lipid content in the body. The functionality of the polypeptide is largely dependent on the informational sequence and physical configuration. Any conformational change on the high cysteine and proline region will affect the binding affinity of the molecule as well as its potency. Peripheral binding is influenced by the two domains, which serve as hinge on the membrane.


AOD9604 is a synthetic peptide that consists of 14 amino acids. Also known as tyr-somatostatin, AOD9604 stimulates lipolysis and suppress lipogenesis without influencing growth or causing insulin resistance. The compound is regarded as a growth hormone analogue. Experimental studies were conducted by the scientists at Monash University to investigate the effects of the compound on obesity. The researchers found that the compound selectively targets obese fat cells but not lean fat cells. Being rich in proline and proteases, AOD9604 exerts several cellular changes in cytoplasm. The hypolipidemic property of the investigative compound is being studied by the research community. The compound’s molecular weight is 1815.1 Daltons and molecular formula is C78H13O23S2.


AOD9604 Chemical Profile


CAS: 221231-10-3
Formula: C207H308N56O58S1
Molecular weight: 1815.1
Peptide purity: > 99.0%
Chain:Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe



What is AOD9604?


AOD9604 is a synthetic peptide that consists 14 amino acids. Also called as tyr-somatostatin, AOD9604 stimulates lipolysis and suppress lipogenesis without influencing growth or causing insulin resistance. The compound is regarded as a growth hormone analog. Experimental studies were conducted by the scientists at Monash University to investigate the effects of the compound on obesity. The researchers found that the compound selectively targets obese fat cells but not lean fat cells. Being rich in proline and proteases, AOD9604 exerts several cellular changes in the cytoplasm. The hypolipidemic property of the investigative compound is being studied by the research community.

The compound’s molecular weight is 1815.1 and the molecular formula is C78H13O23S2.


The studies carried on the peptide AOD9604 for their ability to increase blood glucose and sustain blood insulin, which in turn helps in reduction of lipogenesis a process, which induces depositing of fats on the visceral and peripheral organs. The informational sequence is highly influential in presenting regions of high protein accessibility to the receptors. Research shows that the HGH fragment releasing fats are inhibited by the introduction of the polypeptide. Moreover, it does not induce growth or change food consumption. AOD9604 increases muscle mass, reduce excess adipose tissues in the abdominal area, and increases the lipid content in the body. The functionality of the polypeptide is largely dependent on the informational sequence and physical configuration. Any conformational change on the high cysteine and proline region will affect the binding affinity of the molecule as well as its potency. Peripheral binding is influenced by the two domains, which serve as a hinge on the membrane.


AOD9604 is a synthetic peptide that consists of 14 amino acids. Also known as tyr-somatostatin, AOD9604 stimulates lipolysis and suppresses lipogenesis without influencing growth or causing insulin resistance. The compound is regarded as a growth hormone analog. Experimental studies were conducted by the scientists at Monash University to investigate the effects of the compound on obesity. The researchers found that the compound selectively targets obese fat cells but not lean fat cells. Being rich in proline and proteases, AOD9604 exerts several cellular changes in the cytoplasm. The hypolipidemic property of the investigative compound is being studied by the research community. The compound’s molecular weight is 1815.1 Daltons and the molecular formula is C78H13O23S2. The synthesis of the peptide can be accredited to researchers from Monash University who were looking for uses of growth hormone in alleviating peripheral and visceral fat. Findings from the study showed that a tiny region of the growth hormone is essential in the accentuating development of the lean body. The region was from amino acid number 177 to amino acid number 191.


This is less than 10% of the total peptide size and it is essential to note that this part functions effectively because it enhances ligand to hormone binding. In addition, it has no effect on insulin resistance, growth, development, and mechanism of growth hormone. Growth hormone is important in accentuating cellular division, cell development, and cell maturity. Growth hormone is crucial in regulation and metabolism. In essence, it is effective in alleviating visceral and peripheral fat layers in the adipocytes. When cell death is initiated, waste products are deposited on adipocytes and excreted as waste materials by the system. It is imperative to note that AOD9604 weight loss process does not affect food intake, you can supply a regular diet to the test subject with regular food intake, and the organism will still show weight loss at the end of the experiment. The peptide does not affect the levels of intracellular insulin-like growth factor 1 and it is still in vivo research to ascertain its functionality and use in lipolysis.


AOD9604 Research


Lipolysis and anti-lipogenic abilities of AOD9604 are exceptional, research studies are still underway, and findings have shown that the peptide reduces production of insulin. The most active part of the peptide is rich in proteases and proline residues and depending on the leading sequence or informational sequence affinity and ligand, binding is affected. Conformational change in cytoplasmic band 3 affects two domains and studies reveal that it supports two domains and studies show that ACTH 1-24 has effects on levels of cyclic AMP. The levels of cyclic adenosine monophosphate are usually dependent on the production of aldosterone and angiotensin II. There are findings that human growth hormone has lipolytic properties. However, the mechanism of action has not been clearly understood. There have been various studies to determine how the hormone works to reduce fat cells in the peripheral and visceral organs. The lipolytic activities of this peptide cannot be underestimated because research shows that it can induce chronic in vivo action and this is done via the expression of beta 3-AR receptors.


Moreover, administration of AOD9604 peptide has shown to have a net positive effect on the overall functionality of beta-ARs. The studies show that the administration leads to expression of beta 3-ARs on the adipose tissues of the test subjects. In brown adipose tissues or BAT AOD9604, peptide increases expression of beta 3-AR and this is a new concept because it enhances weight loss. It is imperative to note that administration of the peptide leads to an enhanced expression of beta 3-AR receptors and this is crucial in accentuating weight loss. AOD9604 is vital in contributing to lean body mass and studies done on mice showed that mice treated with the peptide had a significant weight loss. However, administration of the peptide was based on a saline or bacteriostatic expression. The absence of the peptide caused an increase in fat deposition via lipogenesis. However, administration of AOD9604 reduced the amount of fats deposited on peripheral and visceral organs effectively.


Findings from this research showed that is only the presence of AOD9604 that can induce a reduction in mass of the peripheral fat cells. Previous studies done on obese mice showed that it has a net positive effect on fat reduction. AOD9604 was administered to the mice and results monitored closely. Daily weight was recorded and the brains of the mice inspected using modern technology, findings showed that there was an increased activity and production of growth hormone in the anterior lobe of pituitary gland. In addition, an elevated level of growth hormone accentuated weight loss because lipogenesis could not be activated. It is imperative to note that administration of the peptide was not altered because the mice consumed a regular amount of food and that the weight loss seen could only be attributed to the peptide. In addition, placebo mice were treated same as research mice. Food intake was unaltered and their weight levels monitored, findings showed that the mice gained weight while those on AOD9604 peptide recorded a high weight reduction. The mode of action of this peptide is via inhibition of peripheral deposition of fats and cutting nutrient and blood supply to the fat cells.
Human growth hormone and AOD9604 works in synergy with other endogenous hormones to accentuate reduction in adipocytes on visceral and peripheral organs.

Administration of the peptide on obese mice showed that this peptide caused a major reduction in the fat cells. In addition, it was noted that a considerable amount of fat occurred because of AOD9604 even without any change in diet. Reduction in adiposity occurred without any change in caloric intake and this is important because even without changing the diet administration of the peptide could accentuate weight loss. When adiposity gradually reduces it also affects the total weight of the organism because fat cells shrink and die off, therefore, accentuating weight loss. Studies reveal that growth hormone has lipolytic properties and it also as anti-lipogenic features. In this context, it prevents the conversion of excess glucose in the system to glycogen for storage. Conversion of glucose to glycogen affects deposition of fats because energy consumed does not match its intake.


AOD9604 Dosage

One of the most important aspects of any research is dosage, this feature is crucial because any alteration on the dosage level could affect how the test subject will respond to the entire process. It is important to note that variations in concentration, preparation, and mode of administration of AOD9604 peptide will affect the final results. Use of the peptide in different laboratory setting should produce results that match modern science and research. This is an essential aspect of research and development. An experiment should produce predictable results but not necessarily the same. When purchasing peptides for research it is imperative that you put into consideration the quality and purity of the peptide. Effects of the peptide are mediated by expression of an anti-lipogenic gene and this is via expression of beta 3-AR receptors on the different ligand.
The peptide works via the mediation of G-coupled protein receptors binding to adenylate cyclase and this leads to the generation of cyclic adenosine monophosphate. Cyclic adenosine monophosphate, on the other hand, stimulates the synthesis and production of protein kinase A. This enzyme is effective in adding a phosphate group to the proteins by accentuating a lipolytic cascade that incorporates hormone sensitive lipase. In BAT, beta 3-AR activation occurs via uncoupling of various elections on transport chains and this is crucial in accentuating its transport on mitochondrial membrane. Dissipation of electron gradient is crucial in providing a change in energy expenditure. The amount of energy consumed by test organism differs greatly depending on the use of the peptide and deposition of fats on visceral and peripheral organs. The essence of the change in the beta 3 AR gene expression when the peptide is administered will depend on the selective agonist and the mechanism of action that the peptide brings in accentuating weight loss and the breakdown of the brown adipose tissues.