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GHRP-6

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GHRP-6

Availability: In stock

$18.99

Availability: In stock

$18.99
Description

What is GHRP-6?


All the information below is strictly for research purposes only. Under no circumstance should this chemical be used for human consumption.


GHRP-6 is a synthetic met-enkephalin analogue and growth hormone releasing peptide. GHRP-6 contains 6 amino acids including unnatural D-amino acids to facilitate growth hormone release (secretagogue). GHRP-6 administered experimental animals showed significant body weight, muscle growth, glucose metabolic rate, heart and brain functions, according to a study published in the Journal of Clinical Endocrinology and Metabolism. Instead of binding with GHRP-6 receptors, the biomolecule acts at ghrelin receptors. The effects of endogenous GH secretagogues differ from recombinant hGH. Endogenous growth hormones contain 5 isoforms; however, exogenous rHGH contains 20 kDal isoform only. Growth hormones release stimulating property of GHRP-6 reduces fat deposition and body mass. GHRP-6 exerts anti-inflammatory property and promotes liver health. Studies are underway to explore and understand the properties of GHRP-6. The molecular weight is 873.014 and molecular formula is C46H56N12O6.


The growth hormone releasing hormone is composed of both isomeric and natural forms of the amino acids in L and D configurations. The sequence is vital in signaling the body to secrete GH while blocking the activity of somatostatin an inhibitor that prevents optimal release of growth hormone.  Research on the efficiency of the GHRP-6 and other blends are underway to ascertain their potency, half-life, and their synergistic approach. GHRP-6 acts on both the pituitary and hypothalamic sites; however, the primary target of the GHRP-6 is the hypothalamus. GHRP-6 activity is inhibited by somatostatin; however, an increased concentration of the hormone results in the increase of GH released per cell. The mechanism of stimulation of the GHRP-6 is not yet known. Moreover GHRP-6 has a positive feedback mechanism in accentuating the release of Ghrelin a hormone which induces hunger, gastric motility and gastric emptying.


GHRP-6 Chemical Profile


CAS: 87616-84-0
Formula: C46H56N12O6
Molecular weight: 873.01
Peptide purity: > 99.0%
Chain: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2




Click here to read more about GHRP-6




What is GHRP-6?



GHRP-6 is a synthetic metenkephalin analogue and growth hormone releasing peptide. GHRP-6 contains 6 amino acids including unnatural D-amino acids to facilitate growth hormone release (secretagogue). GHRP-6 administered experimental animals showed significant body weight, muscle growth, glucose metabolic rate, heart and brain functions, according to a study published in the Journal of Clinical Endocrinology and Metabolism. Instead of binding with GHRP-6 receptors, the biomolecules acts at ghrelin receptors. The effects of endogenous GH secretagogues differ from recombinant HGH. Endogenous growth hormones contain 5 isoforms; however, exogenous rHGH contains 20 kDal isoforms only. Growth hormones release stimulating property of GHRP-6 reduces fat deposition and body mass. GHRP-6 exerts anti-inflammatory property and promotes liver health. Studies are underway to explore and understand the properties of GHRP-6. The molecular weight is 873.014 and molecular formula is C46H56N12O6.



The growth hormone releasing hormone is composed of both isomeric and natural forms of the amino acids in L and D configurations. The sequence is vital in signaling the body to secrete GH while blocking the activity of somatostatin an inhibitor that prevents optimal release of growth hormone. Research on the efficiency of the GHRP-6 and other blends are underway to ascertain their potency, half-life, and their synergistic approach. GHRP-6 acts on both the pituitary and hypothalamic sites; however, the primary target of the GHRP-6 is the hypothalamus. GHRP-6 activity is inhibited by somatostatin; however, an increased concentration of the hormone results in the increase of GH released per cell. The mechanism of stimulation of the GHRP-6 is not yet known. Moreover, GHRP-6 has a positive feedback mechanism in accentuating the release of Ghrelin a hormone that induces hunger, gastric motility, and gastric emptying.



Growth hormone releasing hexapeptide is vital in blocking activities of somatostatin a peptide produced on somatotrophs on the anterior lobe of pituitary gland. When somatostatin pulses are high pulses of growth hormone are low. It is essential to note that hormonal balance is crucial in maintaining an optimal environment in the production of growth hormone from anterior lobe of pituitary gland. When the level Of GHRP 6 is elevated in the system, it results in a higher growth hormone pulse and the activity of somatostatin is curtailed to its lowest. Activation of GRF neurons is crucial in accentuating release of growth hormone from anterior lobe of pituitary gland. Mechanism of action of the peptide is similar to that of hexarelin and making a blend of the two is vital in attaining optimal capacity. Studies reveal that combining growth hormone releasing hexapeptide and hexarelin can increase production of growth hormone. GHRP 6 is a synthetic hormone and it works on growth hormone secretagogue receptors of GHS-R. An increase in activity of the peptide is essential in accentuating release of growth hormone from anterior lobe of pituitary gland.



GHRP 6 has gained a huge popularity over the past years for its potency in alleviating some conditions and improving muscle mass and enhancing lean body mass. In reality, mechanism of action is through biomimicry, it mimics natural system in releasing growth hormone. In addition, it increases production of ghrelin studies shows that insulin resistance and obesity are some of the common problems associated with increase in weight. A study found out that GHRP 6 has protective effects on hepatocytes, this is vital because liver cells are nourished throughout and altering the system does not affect its functionality. Some data suggests that GHRP 6 has anti-inflammatory effects and it exerts this process on parenchymal cells. In essence, the peptide works on various essential components of a biological system these include



Central nervous system



GHRP 6 works on the central nervous system of test subjects and research shows that there was a significant activity on brain cells of test subjects. In addition, the peptide affects the spinal cord and the brain nerves. This peptide is crucial for coordination and integration of various systems on the test subject.



Pituitary gland



This is a tiny gland that is situated at the bottom of hypothalamus and it is imperative to note that the peptide plays a key role in endocrine related functions such as temperature control, metabolism, and pain relief among other important functions.



The stomach



The digestive system is vital in breaking down food particles into usable material for the body to maintain an optimal functioning. It is essential to note that GHRP 6 is important in accentuating the release of ghrelin a hormone that is beneficial in inducing gastric emptying, gastric motility, and a better digestion in the system.



In essence, growth hormone releasing hexapeptide has the ability to block the functions of somatostatin and it is vital to note that the production of growth hormone is largely affected by presence of somatostatin in the system. Research shows that GHRP 6 helps in maintaining a good homeostasis and activation of intracellular pathways, which as important in producing materials that are crucial for survival. Activation of intracellular signaling is essential in production of several materials that aid the functioning of the system. A new study has revealed that there is a possibility of using growth hormone hexapeptide in alleviating some condition such as hypoxic ischemic attacks among others. Moreover, the peptide is known to accentuate distribution of oxygen in a biological system. Oxygen distribution is crucial because it determines cellular survival, in most cases the cells cannot reproduce if there is no oxygen. In addition, it aids in alleviation of various toxic chemicals in the system.



GHRP 6 and hunger



Leptin is a peptide that plays a crucial role in accentuating satiety. Satiety is an essential aspect because without feeling full the research subject will ingest more food resulting in obesity and in most cases deposition of excess fats to visceral and peripheral parts of the system. Dictated by the relationship with GHRP 6 the peptide is important in enhancing release of growth hormone from pituitary gland and in some cases, the peptide has ability to induce release of insulin like growth factor 1. In the stomach the peptide has shown to posses lipogenic properties which means that it accentuates burning of fats and prevents lipogenesis which a process of fat formation. In addition, it has the capacity to boost production of myoblasts or muscle cells and it is efficient in homeostasis because it improves skeletal muscle growth. According to a recent data tested on animals, functionality of GHRP 6 cannot be underestimated and modern science shows that the peptide could prove to be effective in weight loss.



GHRP-6 and Muscle Repair



The relationship between GHRP 6 and insulin like growth factor 1 has shown that it is essential in enhancing tissue repair and muscle mass. This is the same concept that indicates that the peptide is effective in providing a higher functionality associated with tissue growth. Pituitary gland activity is essential in alleviating fats on visceral and peripheral organs. If these fats are not broken down, they normally lead to obesity. According to research done on obese mice, injection of GHRP 6 peptide is seen to reduce fat deposition and it aids in reducing lipogenesis or generation of fats. When fat breakdown occurs, it leads to strengthening of joints and connective tissues and boosting of immune system. These are essential in building the system up. Moreover, there is enough data to show that GHRP 6 is vital in accentuating various features in a biological system.



It is imperative to note that peptide supplied in the market is solely for research purposes and human consumption is not allowed. According to the studies, the dosage required to elicit reaction is 1.5 mg to 2 mg depending on the weight of test subject and the objectives of the research. GHRP 6 for sale is found in various outlets across the globe and it is important that you find the right outlet to use peptide of high purity and quality. Quality and purity are some of essential factors in research because using a faulty peptide will lead to faulty results. This is vital and results that cannot be reproduced are not trusted in research. It is imperative to note that modern science plays a crucial role in development of newer drugs and other components. Growth hormone plays an essential role in increasing production of binding protein collage. An increase in collagen increases internal cellular tissue repair and according to studies, it also enhances sleeping patterns of the test organism.



Unlike endogenous hormone, GHRP 6 has a higher half-life ant it lasts for 3 hours in an active state. The pulsatile release of growth hormone from anterior lobe of pituitary gland is increased with exposure to GHRP 6 peptide. However, overexposure to this peptide does not lead to any significant increase in hormonal production. There is a certain threshold that when hormone production is at its maximum level any additional peptide does not cause any significant change. Research shows that the peptide increases intracellular desensitization to growth hormone and the response is related to the concentration of the hormone in the system. Administration of growth hormone releasing hexapeptide shows that it can reach to various target organs in the system and it is imperative to note that supraphysiological levels of this hormone play an essential role in accentuating release of growth hormone.




 

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