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MGF C-Terminal

MGF C-Terminal

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MGF C-Terminal

Availability: In stock

$24.98

Availability: In stock

$24.98
Description

What is MGF C-Terminal?


All the information below is strictly for research purposes only. Under no circumstance should this chemical be used for human consumption.


MGF C-Terminal is a growth hormone that is released due to IGF-1 splice variant and stimulation of satellite cells. MGF C-Terminal is also called as IGF-1Ec or mechano growth factor. During healing and tissue re-growth processes, IGF-1 splice variants play a vital role in development and growth of new muscle tissues. During gene splicing mechanisms, IGF-1 gene is spliced to form IGF-1Ec (MGF) and promotes growth of new muscle fibers. C-Terminal end is a specialized sequence of a peptide molecule in which splicing mechanisms takes place and allows the molecule to act independently. In vivo and in vitro studies have demonstrated that MGF C-Terminal possess neuroprotective effects. Facilitated maturation of satellite cells can accelerate cellular recovery and muscle cells formation. The molecular mass of MGF C-Terminal is 2888.16 and molecular formula is C121H200N42O39.


When mechanical overload is introduced on the myoblasts, the insulin like growth factor 1 gene is released and this promotes the differentiation and splicing process. The gene is splice to produce IGF-Ec, which is essential in stimulating satellite cells, when the cells are activated; they accentuate formation of muscle cells from nuclei. The presence of MGF initiates the up regulation of new peptide synthesis, when protein synthesis is up regulated the muscle fibers are healed and there is a regrowth of other muscle cells. Recent studies indicate that when monoclonal antibodies are used to secrete MGF via cell fusion technique, the antibodies recognizes the MGF peptide from the amino acid number 87-111. Moreover, ELISA tests indicate that there is high affinity of the ligand binding to the site of the amino acid 87 to 111.


MGF C-Terminal Chemical Profile


CAS: N/A
Formula: C121H200N42O39
Molecular weight: 2888.16
Peptide purity: > 99.0%
Chain: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys


 

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