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TB-500

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TB-500

Availability: In stock

$49.99

Availability: In stock

$49.99
Description

What is TB-500?


All the information below is strictly for research purposes only. Under no circumstance should this chemical be used for human consumption.


TB-500 is a synthetic form of Thymosin Beta 4 that occurs naturally in animal cells. The peptide is one of the members of 16 related molecules’ ubiquitous family. TB-500 is utilized by the body to improve differentiated endothelial cells functions and associated physiological roles. The molecule acts by regulating the cellular skeleton protein called actin. The latter represents about 10% of the total cellular proteins, vital for cellular and genetic architecture. The synthetic peptide is widely studied for its anti-inflammatory and wound healing properties. Research evidences suggest that TB-500 might be useful for skin and muscle building. Due to low molecular weight, the synthetic peptide is able to migrate to distant organ sites. TB-500 aids keratinocyte and endothelial migration. Speculated to be an up-regulated gene, TB-500 administration accelerates angiogenesis and hematopoiesis by 4-6 times than normal rate. The molecular weight of TB-500 is 4963.44 and molecular formula is C212H350N56O78S.


According to studies, the hormone promotes muscle building, wound healing, and speeds up muscle recovery when it is administered subcutaneously. One of the most important aspects of the TB-500, the central small amino acid long actin-binding domain has cell production and wound healing properties. This is more accentuated by the migration of the keratinocyte and endothelial cells; moreover, it increases the production of extracellular matrix-degrading enzymes. One key mechanism of TB-500 is the regulation of cell building proteins; actin is an essential component in wound healing and production of new cells. TB 500 is vital in cell differentiation, proliferation and maturity, studies also reveal that the functioning o the cells depend on the level of the hormone. Thymosin beta 4 plays a crucial role in the deposition  of collagen thereby reducing inflammation.


TB-500 Chemical Profile


CAS: 77591-33-4


Formula: C212H350N56O78S


Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser


Molecular weight: 4963.44


Peptide purity: > 99.0%







What is TB-500?



TB-500 is a synthetic form of Thymosin Beta 4 that occurs naturally in animal cells. The peptide is one of the members of 16 related molecules’ ubiquitous family. TB-500 is utilized by the body to improve differentiated endothelial cells functions and associated physiological roles. The molecule acts by regulating the cellular skeleton protein called actin. The latter represents about 10% of the total cellular proteins, vital for cellular and genetic architecture. The synthetic peptide is widely studied for its anti-inflammatory and wound healing properties. Research evidence suggests that TB-500 might be useful for skin and muscle building. Due to low molecular weight, the synthetic peptide is able to migrate to distant organ sites. TB-500 aids keratinocyte and endothelial migration. Speculated to be an up-regulated gene, TB-500 administration accelerates angiogenesis and hematopoiesis by 4-6 times than normal rate. The molecular weight of TB-500 is 4963.44 and the molecular formula is C212H350N56O78S.



According to studies, the hormone promotes muscle building, wound healing, and speeds up muscle recovery when it is administered subcutaneously. One of the most important aspects of the TB-500, the central small amino acid long actin-binding domain has cell production and wound healing properties. This is more accentuated by the migration of the keratinocyte and endothelial cells; moreover, it increases the production of extracellular matrix-degrading enzymes. One key mechanism of TB-500 is the regulation of cell-building proteins; actin is an essential component in wound healing and production of new cells. TB 500 is vital in cell differentiation, proliferation, and maturity, studies also reveal that the functioning o the cells depend on the level of the hormone. Thymosin beta 4 plays a crucial role in the deposition of collagen thereby reducing inflammation. Cell proliferation and maturity is an important aspect in replacement of damaged cells and growth of dermal tissues. Studies reveal that indicates that thymosin beta 4 plays an essential role in the deposition of collagen and it improves migration of keratin cells to peripheral organs thereby decreasing inflammation of the site.



The activity of TB 500 is still under research especially for its effectiveness and potency of the peptide actin. Actin is an essential aspect of protein synthesis because it accounts for 10% of total proteins in the system and it has an important aspect in expression and development of genes. The cells bind to receptors and this is essential in causing actin-sequestering molecules in eukaryotic cells, it prevents actin polymerization, and this prevents molecules from binding to different molecules.



TB 500 and blood vessel formation



Research shows that thymosin beta 500 is an essential component in up-regulation of blood vessel formation by over five times. The formation of new blood vessels is essential because it ensures that blood is supplied to different parts of the system and to bring out desired effects on a biological system. Amino acid binding is essential in causing the production of extracellular matrix-degrading system and migration of cells to the cytoskeleton. Migration of endothelial cells and keratin is accentuated by TB 500 and it is important to note that it acts as a catalyst in accentuating production of various components in a biological system. Thymosin beta 500 has forty amino acids in its sequence and the structure of amino acid is essential in triggering repair and regeneration process. The most important aspect to understand about thymosin beta 500 is that it is effective in maneuvering through cells and tissues with ease. Therefore, this peptide is vital in accentuating different aspects in a biological system with ease. In addition, studies reveal that it is important in the formation of protein materials that aid in the formation of blood cells.



TB 500 is essential in healing damaged cells and tissues and addition findings indicate that it plays an essential role in myoblastic formation. This is an important aspect because it aids in muscle recovery, repair of damaged tissues and the formation of blood cells. A synthetic version of thymosin is more active and more potent because the orientation of peptide is geared towards the presentation of binding sites. The versatility of this hormone can be attributed to the structural conformation and orientation of molecules. In addition, TB 500 has anti-inflammatory properties and it is crucial in cell formation. Since the hormone is low in weight, it can pass through cells and tissues and reach target organ easily. Currently, there are studies to determine effectiveness and potency of this peptide in alleviating various conditions such as chronic pain among others. Other postulated benefits of thymosin beta 500 include reduction of alopecia, flexibility, and reduction of inflammation.



Mode of action



Thymosin beta 500 is a naturally occurring substance and it can be found in nearly all animal cells. This peptide is liked to recovery and repair of tissues because it aids in the formation of new blood cells and tissue fibers. Moreover, thymosin beta 500 plays an essential role in the migration of cells from one region to the other. The mechanism of action of this peptide is via positive feedback mechanism to cell-building protein such as actin and when it is unregulated cell proliferation and migration occur easily. In addition, it is effective in healing and repair of damaged tissues. Thymosin beta 500 is used in conditions where there is acute injury or there is an immediate muscle tissue recovery required. Recent research studies show that there are various conditions that the peptide can be used to alleviate these include muscle tears, tendinitis, muscle strains among other connective tissue related injuries. Research shows that the efficacy and potency of this peptide can be enhanced by increasing concentration and blending it with other peptides. Moreover, thymosin beta 500 is effective in accentuating beta cells to produce cells and these cells then migrate to target organ where it causes repair and healing of cells and tissues. There are findings that combining thymosin beta 500 with modified GRF, GHRP 6, or GHRP 2 enhances thymosin beta 500 modes of action and its overall efficacy.





Thymosin beta 500 dosage cycles



Just like any other peptide in the market TB 500 is supplied as a lyophilized or freeze dried powder 2-10 mg. It is imperative to note that for you to achieve results you have to administer the right dosage on the test subject. It is imperative to note that for best results to be achieved it is recommended that you reconstitute a peptide that you will use within a stipulated time only before reconstituting a whole vial. The reconstitution process should use bacteriostatic or saline water. The common research dosage administered to mice is 2mg to 2.5 mg and depending on the objectives of your research. You should administer a peptide that you know will elicit a reaction. Thymosin beta 500 is a shorter fragment of natural thymosin beta 4 and it is imperative that you buy the right peptide because TB-4 is also supplied by unscrupulous vendors as TB 500. TB 4 is produced by thymus gland and concentration is high during childhood and it reduces gradually as the child develops until adulthood where it is nonexistent.



The proteins in this peptide do not bind to receptors because it is quite large and it affects binding sites. It is imperative to note that contrary to other peptides thymosin beta 500 is very effective in accentuating development of new blood cells. In addition, it is very effective in reducing hair loss experienced by males, in most cases areas where hair has turned gray it reverses the process. There are various studies conducted on the efficacy and potency of the peptide in increasing muscles. According to the study thymosin, beta 500 was injected on a horse and monitored. Findings show that it is effective in accentuating production of myoblasts and activation of satellite cells. When these cells are activated they exponentially increase muscle mass. It is essential that when you buy TB 500 you should store it in a cool dry place away from sunlight because sunlight affects its potency and efficacy. In addition, distribution of these cells in a biological system is increased rapidly once TB 500 is administered.



Sunlight is known to cause disintegration of the peptide and it is imperative that when you buy TB 500 peptide you should keep it in a cool dry dark place. The peptide is often supplied as a freeze-dried vial and you should reconstitute amount of peptide that you need for one research. This is crucial because you will avoid contaminating the entire vial when you reconstitute the peptide store it in a freezer and do not expose it to other elements. TB 500 is an important compound in enhancing cellular division, multiplication, and development of the cells. Myoblastic differentiation is an important aspect that should be put into consideration, it aids in healing and repair of damaged cells. This is seen in tendons of mice that were administered. In this research, placebo mice were not infected with TB 500 while test subjected with damaged muscles and tendons were injected with TB 500. Findings showed that the peptide reduced the period needed for the wounds to heal. Moreover, it accentuates production of various cells and tissues that increased muscle mass.